General Product Information
Quality
EURISO-TOP
prides itself on the quality manufacture of deuterated solvents of nuclear
magnetic resonance from the supply of raw materials right up until arrival at
your laboratory.
Our
newly renovated laboratory is situated on the site of the Atomic Energy
Commission (AEC) in Saclay (France). Our continually updating methods of
production can be attributed to the expertise of the AEC scientists, who are
among the pioneers of such techniques, and who have contributed significantly
to theoretical advances in spectroscopy.
Our
solvent-specific production units and the skills of our experienced teams allow
us to guarantee top quality products with the highest level of chemical purity
and isotopic enrichment. Rigorous checks are made at all stages of the chain in
our laboratories, allowing us to ensure the consistently high quality of our
solvents to meet your requirements.
Production
Supply of raw materials
Solvents
and reagents with a high chemical purity are selected from audited suppliers
and tested before acceptance.
Quality control and
in-process control
Our
production and distillation units are automated and function under an inert nitrogen
atmosphere. During the production and distillation processes and at the time of
batch release, chemical and isotopic purity are carefully assessed with our 400
MHz NMR spectrometer. Traces of water are quantified by the Karl Fischer method
and any non-protonated impurities by gas chromatography. Tests are routinely
carried out for acidity and lack of phosgene in our chlorinated solvents.
Packaging
Supply of packaging
materials
We
select the best containers, vials or ampoules from the suppliers to the
pharmaceutical industry and test them to ensure adequate protection against
deterioration or contamination of our solvents.
Process line clearance
Our
laboratory is filled with automated bottle and ampoule conditioners which clean
according to strict internal procedures and are validated so as not to
compromise on quality. The containers are then carefully dried to prevent
pollution of the solvent through remaining traces of water.
In process-control and
batch release of finished products
Before,
during and after the packaging, conducted in an inert atmosphere of nitrogen
and argon, the chemical and isotopic purity is then carefully checked again
with our 400 MHz NMR spectrometer. Traces of water are again quantified by the
Karl Fischer method.
Sample
Bank
Each
package is given a batch number for constant traceability, allowing us to
process your queries quickly and accurately.
Stability
Study
Our
stability studies have allowed us to establish optimal storage conditions for
the majority of our solvents, details of which are made available.
Environment
and Security
EURISO-TOP
has been committed to reducing its liquid, solid and gaseous emissions for
several years. Risk analyses and working environment checks allow us to
carefully pinpoint the presence of VOCs and to ensure maximum safety at work
for our teams. Our chemical waste is taken care of by leaders in the field of treatment
and the collection is carefully organized.
EURISO-TOP
is actively involved in recycling metals, wood, plastic, glass and card every
day. For transportation, recyclable card and the standardized use of other
‘green’ cushioning materials help to extend our involvement in the
environmental chain with the assistance of our service carriers.
