Nucleic acids (includes DNA and RNA) are necessary building blocks of living organisms, being fundamentally important to a multitude of cellular processes. Compositionally, nucleic acids are comprised of nucleobases (e.g., adenine, cytosine), nucleosides (e.g., adenosine, guanosine), and nucleotides (e.g., ATP, CDP). These compounds may be used as starting materials in the enzymatic or chemical synthesis of RNA and DNA. Applications of stable isotope labeled nucleic acids are broad, ranging from the evaluation of protein structure and dynamics to the evaluation of nucleic acids as potential biotherapies, such as RNA therapeutics.
To assist with RNA/DNA-related NMR- Eurisotop offers a large selection of various stable isotope-labeled compounds. We also offer sets of deoxyribonucleoside monophosphates (dNMPs), deoxyribonucleoside triphosphates (dNTPs), and ribonucleoside triphosphate (rNTPs) in different unit configurations for ease of use.